Laboratory Tested Solvent
This product is intended for use as a mild solvent only. The choice of the process used in the various applications is the sole responsibility of the user. Please consult with your veterinarian as to the proper use of DMSO.
DMSO (dimethyl sulfoxide) Liquid is recommended as a topical application to reduce acute swelling due to trauma.
Off-Label Administration and Dosage:
Recommended as a topical application to reduce acute swelling due to trauma.
CONSULT YOUR PHYSICIAN OR VETERINARIAN BEFORE USING THIS PRODUCT ON A PERSON OR ANIMAL. Any use other than as a solvent is considered off-label use.
DMSO Liquid is to be administered topically to the skin over the affected area.
Dogs - Liberal application should be administered three to four times daily. Total daily dosage should not exceed 20 mL. Total duration of therapy should not exceed 14 days.
Horses - Liberal application should be administered two to three times daily. Total daily dosage should not exceed 100 mL. Total duration of therapy should not exceed 30 days.
Side Effects:
In general, adverse reactions are local, and while they may prove to be annoying to some patients, they are usually not of a serious nature. Upon topical application, an occasionally animal may develop transient erythema, associated with local burning or smarting. Even when erythema or vesiculation occurs, they are self-limiting reversible states, and not necessarily an indication to discontinue medication. Dryness of the skin and an oyster-like breath odor have been reported. These effects are temporary and are not considered to be of serious consequence. Changes in the refractive index of the lens of the eye and nuclear cataracts have been observed in animals, with the use of this drug. This appears to be related to dosage and duration of therapy.
Precaution and Contraindications:
Contact between DMSO Liquid and the skin should be avoided. Rubber gloves should be worn while applying this drug. Forceps and swabs may be used to facilitate application. If absorbed through the skin, DMSO Liquid will cause odorous breath and unpleasant mouth taste. Mild sedation or drowsiness, sensations of warmth, burning, irritation, itching and mild erythematous localized or generalized dermatitis have been reported in some persons following exposure to DMSO Liquid. Treatment of such side effects is symptomatic. Consult a physician immediately if adverse effects appear.
DMSO Liquid may mask certain disease signs such as seen in fractures, etc.; this does not obviate the need for specific therapy in such conditions.
Since DMSO Liquid effectively alters the biologic membrane, it will in some cases facilitate the systemic absorption of other topically applied drugs and may have a potentiating effect on drugs administered systemically.
DMSO Liquid should be judiciously used when administered in conjunction with other pharmaceutical preparations, especially those affecting the cardiovascular and central nervous systems.
DMSO Liquid may enhance the absorption of other materials into the skin. The veterinarian should make certain that other medications are not present prior to its application.
Keep DMSO Liquid out of the reach of children.
DMSO Liquid is recommended for topical application only. DO NOT ADMINISTER BY ANY OTHER ROUTE.
DMSO Liquid should not be used under occlusive dressings.
DMSO Liquid is contraindicated in horses and dogs intended for breeding purposes.
DMSO Liquid is a potent solvent and may have a deleterious effect on fabrics, plastics and other materials. Care should be taken to prevent physical contact with DMSO Liquid.
DMSO Liquid should not be administered to horses that are to be slaughtered for food.
CAUTION: HYGROSCOPIC. CLOSE CAP TIGHTLY AFTER USE. AVOID FREEZING. DUE TO THE RAPID PENETRATION ABILITY OF DMSO LIQUID, RUBBER GLOVES SHOULD BE WORN WHEN APPLYING THIS PRODUCT.
