Pala-Tech Vitamin K1 25mg

Cautions: Temporary resistance to prothrombin-depressing anticoagulants may result, especially when larger doses of phytonadione are used. It is recommended that Pala-Tech Vitamin K1 Chewable Tablets be used in follow-up therapy only after administration of Vitamin K1 injection and hospitalization is no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally.

Phytonadione will not counteract the anticoagulant action of heparin. Repeated large doses of Vitamin K1 are not warranted in hepatic disease if the response to the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K1.